In La Fin des Certitudes, Ilya Prigogine suggested a new principle of uncertainty, resulting not from the limits of human knowledge but from the nature of physical reality itself which seems to be essentially undetermined.
In this collective work, Prigogine has brought together some twenty scientists and philosophers and asked them to consider uncertainty first in physics and chemistry, then in biology and the social sciences, and finally in the cultural arena.
The conclusions of what may well become the manifesto of a new science are drawn by Isabelle Stengers.

Ilya Prigogine, winner of the Nobel Prize for chemistry, teaches at Brussels’ Université Libre.